ky体育在线登陆SCI文獻上線-上海信帆

ky体育在线登陆SCI文獻上線-上海信帆

熱烈祝賀老師訂購我司ky体育在线登陆，SIC文章發表成功!發表期刊WJG.

WJG在眾(zhong) 多消化類期刊中惟一進入SCI-E行列-美國科學情報研究所(Institute for Scientific Information,ISI)2000年度《期刊引用報告》WJG全稱是世界胃腸病雜誌，被SCI收錄了。

文章標題：

P-selectin glycoprotein ligand 1 deficiency prevents development of acute pancreatitis by attenuating leukocyte infiltration

摘要：BACKGROUND Acute pancreatitis(AP) is rapid-onset pancreatic inflammation that causes local and systemic inflammatory response syndrome(SIRS) with high morbidity and mortality, but no approved therapies are currently available. P-selectin glycoprotein ligand 1(PSGL-1) is a transmembrane glycoprotein to initiate inflammatory responses. We hypothesized that PSGL-1 may be involved in the development of AP and would be a new target for the treatment of AP.AIM To investigate the role and mechanism of PSGL-1 in the development of AP.METHODS The PSGL-1 expression on leukocytes was detected in peripheral blood of AP patients and volunteers. Pancreatic injury, inflammatory cytokines expression, and inflammatory cell infiltration was measured in AP mouse models induced with PSGL-1 knockout(PSGL-1-/-) and wild-type(PSGL-1+/+) mice. Leukocyteendothelial cell adhesion was measured in a peripheral blood mononuclear cell(PBMC)-endothelial cell coculture system.RESULTS The expression of PSGL-1 on monocytes and neutrophils was significantly incre

文章中使用我司試劑盒為(wei) ：IL-1beta elisa kit   IL-6  elisa kit 

上海信帆生物供應的ky体育在线登陆可用於(yu) 測定血清，血漿，細胞上清液，組織等液體(ti) 樣本的含量，靈敏度高，質量穩定，深受廣大科研用戶青睞。如果想谘詢更多信息，可以聯係ky体育亚洲杯。

ky体育在线登陆SCI文獻上線-上海信帆